If you mean can I change a crawl space into to a full basement, any thing can be done if you have enough money. It would be a really big under taking to do it. The house would need to be supported while it's being dug out and a whole new foundation and footing would have to be done. There would have to be one great big hole dug out in the yard made into a ramp so a bocat could get in to remove the dirt, Then a new slab floor would need to be pored after the plumbings in.
Not A DIY job at all.
Just the plumbing and pit so water can be pumped up and out would be over $2,000.