If I was going to close up a hole on my house, I would seal it with at least some tyvek over the hole ,behind the siding. I would also layer it so when it rains it sheds the water that does get behind the vinyl, down the wall. Then I would tape it with tyvek or housewrap tape just to seal the wind out.
That's my

Good luck, that voice called the "wife" never goes away.