I have these chemical gloves.
Lye is apparently Sodium Hydroxide.
http://www.homedepot.com/p/Everbilt-Long-Cuff-Neoprene-Glove-Large-EB00131-L/203613745
They go about halfway up the arm. They are listed as "Good" protection from Sodium Hydroxide. The only step up is Excellent, which apparently is a vinyl glove of some sort. HD doesn't carry that kind of stuff in the store, however.
I threw on a simple P100 strapped face mask just for the basic crawling around in the crawlspace today setting off the fumigators. Man, after 5 minutes, I could feel the general humidity and atmosphere down there. It was only about 11am and the sun wasn't even fully up yet. Maybe in the early 80's at most. The air keeps it cooler down there when running, but when off, it is pretty interesting down there. Seemed almost hard to breathe after a bit of time. I'll be taking a lot of periodic breaks.
I was reading some of the stuff about lye, though...I came across this.
"Caustic lye products pose other dangers to surfaces. They can dissolve substances to the user's advantage, such as hair clogs in a shower drain, as well as to the user's detriment, such as the adjacent shower curtain. In fact, these products can damage and corrode paint, metal, cloth, plastic and especially skin. It can be so reactive that, in its solid form, it should be kept away from metals, such as aluminum, and the open air. It usually is non-combustible when dry, but it could ignite and cause a fire when mixed with water."
Am I going to get a boom if I throw this stuff in powder form in a wet hole? Pretty sure there's a lot of aluminum in that HVAC system...makes me kind of iffy.